Placenta related pathogenic factors for preeclampsia
نویسندگان
چکیده
منابع مشابه
Placenta related pathogenic factors for preeclampsia
Preeclampsia (PE) is a life-threatening complication of pregnancy. The precise origin of PE remains obscure. Placenta has been considered to play a central role in its pathology. Here we present a brief overlook of placenta related pathogenic factors that might be involved in the pathology changes of PE. A series of factors that correlated with placenta pathology have been regarded attributed t...
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Background. Mitofusin 2 (Mfn2) is a novel mitochondrial protein that is implicated in cellular proliferation and metabolism; however, the role of Mfn2 in preeclampsia (PE) remains unknown. This study aimed to explore the relationship between Mfn2 and PE. Method. Preeclamptic and normal pregnancies were enrolled in a comparative study. The expression of Mfn2 in placenta was detected by qRT-PCR. ...
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During fetal development, the human placenta undergoes high levels of both angiogenesis and vasculogenesis. Additionally, the developing placenta undergoes a process of vascular mimicry (referred to as pseudovasculogenesis) as cytotrophoblasts convert from an epithelial to an endothelial phenotype. The initiation, maturation, and maintenance of the placental vasculature are of critical importan...
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1 Acute maternal complications include eclampsia, stroke, placen-tal abruption, disseminated intravascular coagulation, HELLP (hemolysis, elevated liver enzymes, low platelets), liver hemorrhage or rupture, pulmonary edema, adult respiratory distress syndrome, acute renal failure, and death. 2 Preeclampsia complications account for more than 50 000 maternal deaths annually. 2,3 In developing co...
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BACKGROUND The correlation between gestational hypertension-preeclampsia (GH-PE) and placenta previa (PP) is controversial. Specifically, it is unknown whether placenta previa has any effect on the various types of preeclampsia (PE), and the role PP with concurrent placenta accreta (PA) play in the occurrence of GH-PE are not well understood. OBJECTIVE The aim of this study was to identify th...
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ژورنال
عنوان ژورنال: Open Journal of Obstetrics and Gynecology
سال: 2012
ISSN: 2160-8792,2160-8806
DOI: 10.4236/ojog.2012.24072